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Related Experiment Videos

Thyroid function screening in psychiatric patients.

K L Cohen, M E Swigar

    JAMA
    |July 20, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Thyroid function abnormalities are common in psychiatric patients, with many experiencing temporary stress-induced hyperthyroidism or unclear acute hypothyroidism. Thyroid screening is valuable for this population.

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    Area of Science:

    • Endocrinology
    • Psychiatry
    • Clinical Medicine

    Background:

    • Thyroid dysfunction can manifest with psychiatric symptoms.
    • Screening for thyroid abnormalities in psychiatric inpatients is recommended.

    Purpose of the Study:

    • To investigate the prevalence of thyroid function abnormalities in newly admitted psychiatric patients.
    • To characterize the nature and course of identified thyroid abnormalities.

    Main Methods:

    • Assessed thyroid function tests in 480 newly admitted psychiatric patients.
    • Monitored estimated free thyroxine (EFT4) levels over time.
    • Diagnosed primary and secondary thyroid disorders.

    Main Results:

    • Elevated EFT4 (acute stress hyperthyroidism) observed in 9% of patients, often resolving spontaneously within two weeks.

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  • Decreased EFT4 (acute hypothyroidism) observed in 9% of patients, with unclear etiology and spontaneous normalization in some.
  • Low yield of new primary hyperthyroidism/hypothyroidism cases, but eight presumptive secondary hypothyroidism diagnoses.
  • Nine patients with known thyroid disease had inadequate or excessive replacement therapy.

    • Conclusions:

    • Thyroid function abnormalities are prevalent in psychiatric patients.
    • Acute stress hyperthyroidism is a common transient finding.
    • Thyroid function screening is clinically valuable in psychiatric settings.