Peroxidase activity in non-parenchymal cells isolated from rat liver: a cytochemical study

The cytochemical demonstration of endogenous peroxidase activity has been used as a marker for the Kupffer cells present in a heterogeneous population of non-parenchymal cells isolated from normal rat liver by perfusion and enzymatic digestion. Peroxidase activity was present in the cytoplasm of a greater proportion of cells than were activities of acid phosphatase and non-specific esterase. The value of endogeneous peroxidase as a marker for the Kupffer cell is discussed.