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Secondary renal neoplasms: an autopsy study.
Southern Medical Journal
|July 1, 1979
Summary
Renal metastases occurred in 7.2% of cancer deaths, with lung and breast cancers being the most common primary sources. Most metastases were small and widespread, limiting clinical detection.
Area of Science:
- Oncology
- Pathology
- Nephrology
Background:
- Malignant diseases frequently metastasize to various organs.
- The kidney is a potential site for secondary tumor deposits.
Purpose of the Study:
- To investigate the incidence and characteristics of renal metastases.
- To identify common primary tumor types associated with renal metastases.
Main Methods:
- Retrospective review of 11,328 autopsy records from patients deceased from malignant disease.
- Analysis of cases with confirmed renal metastases.
Main Results:
- Renal metastases were identified in 816 cases (7.2%).
- Most common primary tumors included lung, breast, and skin (melanoma).
- Metastases were typically hematogenous, multiple, bilateral, <3 cm, and spread throughout the renal parenchyma.
Conclusions:
- Renal metastases are a significant finding in cancer autopsies.
- The small size of most renal metastases often precludes clinical detection.
- Awareness of primary tumor types can aid in suspecting renal involvement.