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[Cell-mediated immunity after blocking of the H2 lymphocyte receptors]
Bollettino Dell'Istituto Sieroterapico Milanese
|March 31, 1979
Abstract:
The effects of cimetidine have been evaluated in 10 normal subjects on cutaneous delayed reactions in vivo, and on E rosette forming cells in vitro, in order to define the significance of the lymphocytes H2 receptors in cell-mediated immunity. The results show the immuno-suppressive activity of histamine, but do not allow us to hypothesize an immuno-regulatory action of cimetidine.