Related Experiment Video
Updated: Jul 17, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Males with chronic myeloid leukemia and the 45, XO, Ph1 chromosome pattern
Abstract:
Two cases of chronic myeloid leukemia in which the cytogenetic clone was 45, XO, Ph(1) are described and compared with 20 cases recorded in the literature. The 45, XO line is peculiar to the leukemic cells and is not a manifestation of constitutional mosaicism. It probably arises from a 46, XY, Ph(1) line by loss of the Y chromosome. Because of the few cases reported, one cannot be certain that these men have a better prognosis, although the median survival time suggests that this is so. Infertility is not part of this disorder.
More Related Videos
Related Concept Videos
Pedigree Analysis
X-linked Traits
Sex-linked Disorders
X-Inactivation
X and Y Chromosomes
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
The Ratio of X Chromosome to Autosomes
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...

