Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prognosis after initial myocardial infarction: the Framingham study.

W B Kannel, P Sorlie, P M McNamara

    The American Journal of Cardiology
    |July 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clinical trials and epidemiological studies.

    Clinical trials (London, England)·2006
    Same author

    Arterial distensibility and physical activity in the ARIC study.

    Medicine and science in sports and exercise·2001
    Same author

    Neighborhood of residence and incidence of coronary heart disease.

    The New England journal of medicine·2001
    Same author

    Respondent bias in the collection of alcohol and tobacco data in American Indians: the Strong Heart Study.

    American Indian and Alaska native mental health research (Online)·2001
    Same author

    Occupational hierarchy, economic sector, and mortality from cardiovascular disease among men and women. Findings from the National Longitudinal Mortality Study.

    Annals of epidemiology·2001
    Same author

    Trends in plasma cholesterol levels in the atherosclerosis risk in communities (ARIC) study.

    Preventive medicine·2000
    Same journal

    Real-World Effectiveness and Tolerability of Sacubitril/Valsartan in Octogenarian Patients With Heart Failure: Results From the PARACHUTER Study.

    The American journal of cardiology·2026
    Same journal

    ECG-Guided Conduction Pathways as a Lever to Shorten Post-TAVI Hospitalization.

    The American journal of cardiology·2026
    Same journal

    Cystatin-C versus creatinine and kidney function in heart failure with preserved ejection fraction: a SOGALDI-PEF analysis.

    The American journal of cardiology·2026
    Same journal

    Balloon-expandable versus Self-expanding Valves in Patients with Small Aortic Annuli Undergoing Transcatheter Aortic Valve Replacement.

    The American journal of cardiology·2026
    Same journal

    Drug-Coated Balloons versus Drug-Eluting Stents following Coronary Atherectomy in Severely Calcified Lesions: A Systematic Review and Meta-Analysis.

    The American journal of cardiology·2026
    Same journal

    Prehospital Statin Therapy and Outcomes in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

    The American journal of cardiology·2026
    See all related articles

    Men and women experiencing myocardial infarction face significant long-term risks. Women have a worse prognosis after myocardial infarction, with higher early mortality and reinfarction rates than men.

    Area of Science:

    • Cardiology
    • Epidemiology
    • Public Health

    Background:

    • Coronary heart disease (CHD) remains a leading cause of mortality.
    • Understanding the long-term prognosis after myocardial infarction (MI) is crucial for patient management and public health strategies.

    Purpose of the Study:

    • To investigate the long-term mortality and morbidity following recognized and unrecognized myocardial infarctions in a large cohort.
    • To compare the prognosis of myocardial infarction between men and women.

    Main Methods:

    • Prospective cohort study of 5,127 initially CHD-free individuals from the Framingham cohort.
    • Follow-up over 20 years to ascertain myocardial infarctions, subsequent mortality, and morbidity (angina, reinfarction, congestive heart failure, sudden death).

    Related Experiment Videos

    Main Results:

    • One in five men with a first MI died within 1 year; mortality was 14 times higher than in those without CHD.
    • In men surviving the first year, 5-year mortality risk was four times that of the general population.
    • Women experienced higher early mortality and were more prone to reinfarction (40% within 5 years) compared to men (13%).
    • Congestive heart failure affected 14% of men within 5 years, with a 50% mortality rate once it ensued.

    Conclusions:

    • Myocardial infarction significantly increases long-term mortality and morbidity risk for both men and women.
    • Women face a distinctly worse prognosis after myocardial infarction compared to men, particularly regarding early mortality and reinfarction.
    • Recognized and unrecognized myocardial infarctions have similar long-term survival rates, highlighting the importance of identifying all MIs.