Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Phagocytic myeloma cells.

J H Fitchen, S Lee

    American Journal of Clinical Pathology
    |June 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    This study describes a rare case of multiple myeloma where cancer cells exhibited phagocytosis, engulfing various blood cells and particles. This unusual finding offers new insights into myeloma cell behavior and potential therapeutic targets.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Protective immunity against murine hepatitis virus (MHV) induced by intranasal or subcutaneous administration of hybrids of tobacco mosaic virus that carries an MHV epitope.

    Proceedings of the National Academy of Sciences of the United States of America·1999
    Same author

    Studies of coat protein-mediated resistance to tobacco mosaic tobamovirus: correlation between assembly of mutant coat proteins and resistance.

    Journal of virology·1997
    Same author

    Future applications of oral fluid specimen technology.

    The American journal of medicine·1997
    Same author

    Virucidal activity of an oral fluid human immunodeficiency virus-1 antibody preservative.

    The American journal of medicine·1997
    Same author

    Evaluation of a system using oral mucosal transudate for HIV-1 antibody screening and confirmatory testing. OraSure HIV Clinical Trials Group.

    JAMA·1997
    Same author

    Use of plant viruses for delivery of vaccine epitopes.

    Annals of the New York Academy of Sciences·1996
    Same journal

    Invasive urothelial carcinoma in association with surface low-grade papillary urothelial carcinoma: clinical and pathologic insights from a rare entity.

    American journal of clinical pathology·2026
    Same journal

    CEACAM1 expression by immunohistochemistry in B-cell lymphomas and plasma cell myeloma.

    American journal of clinical pathology·2026
    Same journal

    Comprehensive multicriteria life cycle assessment of biopsy processing in a surgical pathology department.

    American journal of clinical pathology·2026
    Same journal

    Prognostic significance of Myb protein and its downstream target genes in lacrimal gland adenoid cystic carcinoma.

    American journal of clinical pathology·2026
    Same journal

    Mismatch repair protein "nonclassic expression loss" pattern in colorectal cancer: an important staining pattern that is not well understood.

    American journal of clinical pathology·2026
    Same journal

    Musculoskeletal pain in medical laboratory personnel: a cross-sectional study.

    American journal of clinical pathology·2026
    See all related articles

    Area of Science:

    • Hematology
    • Oncology
    • Cell Biology

    Background:

    • Multiple myeloma is a cancer of plasma cells, typically characterized by uncontrolled proliferation.
    • Phagocytosis is a cellular process crucial for immune response and tissue homeostasis, usually performed by specialized cells like macrophages.

    Observation:

    • A unique case of multiple myeloma presented with myeloma cells demonstrating significant phagocytic activity.
    • These myeloma cells were observed to engulf erythrocytes, erythrocytic precursors, lymphocytes, and platelets.

    Findings:

    • In vitro experiments confirmed the phagocytic capacity of myeloma cells through the ingestion of latex particles.
    • This indicates an atypical functional characteristic of myeloma cells in this specific patient.

    Related Experiment Videos

    Implications:

    • The phagocytic nature of myeloma cells may influence disease progression and response to therapy.
    • Understanding this aberrant cell behavior could open new avenues for targeted treatments in multiple myeloma.