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Related Experiment Videos

Lymphatic invasion in pigmented nevi.

M E Bell, D P Hill, M K Bhargava

    American Journal of Clinical Pathology
    |July 1, 1979
    PubMed
    Summary

    In five cases of pigmented nevi, nevus cells were found invading endothelial-lined spaces. This finding is significant for understanding nevus cell migration and its relation to lymph node involvement.

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    Area of Science:

    • Dermatopathology
    • Surgical Pathology

    Background:

    • Pigmented nevi are common skin lesions.
    • Understanding the behavior and potential spread of nevus cells is crucial in dermatopathology.

    Purpose of the Study:

    • To investigate the presence and significance of nevus cells invading endothelial-lined spaces in pigmented nevi.
    • To correlate this finding with existing literature on nevus cells in lymph nodes.

    Main Methods:

    • Review of 124 pigmented nevi cases registered between July 1958 and May 1969.
    • Serial sectioning and microscopic examination of identified cases.

    Main Results:

    • Nevus cells invading endothelial-lined spaces were identified in five out of 124 cases.
    • The observed invasion suggests a potential pathway for nevus cell dissemination.

    Conclusions:

    • The invasion of endothelial-lined spaces by nevus cells is a notable histological finding.
    • This finding warrants further consideration in the context of nevus cell behavior and potential metastatic pathways.

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