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Related Experiment Videos

Inverted follicular keratosis.

J W Sassani, M Yanoff

    American Journal of Ophthalmology
    |June 1, 1979
    PubMed
    Summary

    Inverted follicular keratosis is a benign skin lesion that can mimic malignancy. This review of 17 cases found no recurrences after surgical removal, indicating a favorable prognosis.

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    Area of Science:

    • Dermatopathology
    • Surgical Pathology

    Background:

    • Inverted follicular keratosis (IFK) is a rare, benign skin neoplasm.
    • IFK is frequently misdiagnosed clinically and histopathologically as a malignant lesion.
    • Histological features include squamous eddies, acantholysis, acanthosis, and hyperkeratosis.

    Purpose of the Study:

    • To evaluate the clinical and histopathological characteristics of inverted follicular keratosis.
    • To assess the recurrence rate of IFK after surgical excision.

    Main Methods:

    • Retrospective review of 17 cases diagnosed with inverted follicular keratosis.
    • Analysis of patient demographics, clinical presentation, surgical procedures, and follow-up data.

    Main Results:

    • The median patient age at surgery was 69 years.
    • Follow-up data were available for 14 cases.
    • No recurrences of IFK were observed in the cases with follow-up.

    Conclusions:

    • Inverted follicular keratosis is a benign entity with a low risk of recurrence after complete surgical excision.
    • Accurate histopathological diagnosis is crucial to differentiate IFK from cutaneous malignancies.
    • Surgical management appears to be curative for IFK.

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