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Haemorrhage responsive to vitamin K in a 6-week-old infant

A M Minford, O B Eden

    Archives of Disease in Childhood
    |April 1, 1979
    PubMed

    Insights

    A breast-fed infant experienced bleeding after a procedure due to a vitamin K deficiency. Testing prothrombin time or giving vitamin K is recommended for breast-fed infants to prevent bleeding complications.

    Area of Science:

    • Pediatrics
    • Neonatology
    • Hematology

    Background:

    • Vitamin K is essential for blood clotting.
    • Breast-fed infants may be at risk for vitamin K deficiency.
    • Coagulation abnormalities can lead to serious complications.

    Observation:

    • A 6-week-old exclusively breast-fed infant presented with vomiting, jaundice, and irritability.
    • Hemorrhage occurred following a lumbar puncture procedure.
    • A coagulation abnormality was identified, which resolved after vitamin K administration.

    Findings:

    • The infant's coagulation abnormality responded effectively to vitamin K treatment.
    • This suggests a potential vitamin K deficiency as the underlying cause.
    • Invasive procedures in this age group carry a risk of bleeding complications.

    Implications:

    • Routine prothrombin time estimation before invasive procedures in exclusively breast-fed infants is advisable.
    • Prophylactic vitamin K administration should be considered for breast-fed infants when vitamin K intake is uncertain.
    • Early identification and management of coagulation abnormalities are crucial for infant health.

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