Combined multiple-valve procedures: a five-year experience with 125 patients.

Area of Science:

• Cardiovascular Surgery
• Cardiac Valve Disease
• Surgical Outcomes

Background:

• Combined multiple-valve procedures are complex cardiac surgeries.
• Assessing early and late outcomes is crucial for patient management.

Purpose of the Study:

• To evaluate the early and late mortality and functional outcomes of patients undergoing combined multiple-valve operations.

Main Methods:

• Retrospective analysis of 128 operations in 125 patients for combined multiple-valve procedures.
• Inclusion of hemodynamic parameters in early mortality analysis.
• Long-term follow-up of early survivors.

Main Results:

• Overall early mortality was 16%, with highest rates for mitral and tricuspid valve disease (28.5%).
• Hemodynamic factors significantly differed between survivors and non-survivors.
• Late mortality was 11.2% among early survivors, with 85% showing functional improvement.
• Actuarial 5-year survival for early survivors was 75%.

Conclusions:

• Combined multiple-valve surgery has substantial early risks, influenced by specific valve combinations and hemodynamic status.
• Despite early risks, long-term survival and functional status improve significantly for survivors.
• Risk stratification and management of hemodynamic parameters are vital for optimizing outcomes in these complex cardiac procedures.