Antigenic competition and genetic control of the immune response. A hypothesis for intramolecular competition

A dual altered peptide ligand inhibits myasthenia gravis associated responses by inducing phosphorylated extracellular-regulated kinase 1,2 that upregulates CD4+CD25+Foxp3+ cells.

Scandinavian journal of immunology·2007

MHC class I expression regulates susceptibility to spontaneous autoimmune disease in (NZBxNZW)F1 mice.

Lupus·2005

Autoantibodies to a NR2A peptide of the glutamate/NMDA receptor in sera of patients with systemic lupus erythematosus.

Annals of the rheumatic diseases·2005

Amelioration of lupus manifestations by a peptide based on the complementarity determining region 1 of an autoantibody in severe combined immunodeficient (SCID) mice engrafted with peripheral blood lymphocytes of systemic lupus erythematosus (SLE) patients.

Clinical and experimental immunology·2004

Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 female mice are associated with specific reduction of IgG3 autoantibodies.

Annals of the rheumatic diseases·2003

Modulation of autoreactive responses of peripheral blood lymphocytes of patients with systemic lupus erythematosus by peptides based on human and murine anti-DNA autoantibodies.

Clinical and experimental immunology·2003

SPRY2 mediates fibroblast dysfunction and impaired wound healing in diabetic foot ulcers by blocking the Ras/MAPK axis.

Cellular immunology·2026

Therapeutic attenuation of orbital adipogenesis via M2 macrophage exosomes: A dual inhibition of oxidative stress and autophagy.

Cellular immunology·2026

Analysis of changes in the phenotypic profile and frequencies of peripheral blood myeloid-derived suppressor cells in patients with endometrial cancer before and after surgical treatment.

Cellular immunology·2026

Is there a role for B cells in Alzheimer's disease?

Cellular immunology·2026

TNF and CD107a-dominated enhanced effector responses of CD8+ MAIT cells to Escherichia coli stimulation in patients with aplastic anemia.

Cellular immunology·2026

Hemoglobin-based oxygen carriers promote the expression of antiviral defense genes in bone marrow leukocytes.

Cellular immunology·2026

Impella Versus Intra-aortic Balloon Pump in Cardiogenic Shock: Arrhythmias, Bleeding Complications, and In-Hospital Outcomes in a Propensity-Matched Analysis of the National Inpatient Sample.

Cureus·2026

Unsupervised Machine Learning of Intrapancreatic Fat Deposition Reveals Distinct Clinical Phenotypes: A CT Study.

Diabetes, metabolic syndrome and obesity : targets and therapy·2026

Predictive value of stress-induced hyperglycemia for 28-day all-cause mortality in ICU patients with sepsis: a MIMIC-IV-based retrospective cohort study.

Clinics (Sao Paulo, Brazil)·2026

Layered immune biomarker monitoring in IgA nephropathy: from mucosal IgA dysregulation to precision therapeutic response assessment.

Frontiers in medicine·2026

Gastrointestinal Histoplasmosis Mimicking Intestinal Tuberculosis and Crohn's Disease: Ileocecal Involvement in an Immunocompetent Host.

Clinical case reports·2026

Peripheral immune phenotyping identifies an immunosuppressed sepsis endotype with potential relevance for immune stratification.

Frontiers in immunology·2026

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Antigenic competition and genetic control of the immune response. A hypothesis for intramolecular competition

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A dual altered peptide ligand inhibits myasthenia gravis associated responses by inducing phosphorylated extracellular-regulated kinase 1,2 that upregulates CD4+CD25+Foxp3+ cells.

MHC class I expression regulates susceptibility to spontaneous autoimmune disease in (NZBxNZW)F1 mice.

Autoantibodies to a NR2A peptide of the glutamate/NMDA receptor in sera of patients with systemic lupus erythematosus.

Amelioration of lupus manifestations by a peptide based on the complementarity determining region 1 of an autoantibody in severe combined immunodeficient (SCID) mice engrafted with peripheral blood lymphocytes of systemic lupus erythematosus (SLE) patients.

Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 female mice are associated with specific reduction of IgG3 autoantibodies.

Modulation of autoreactive responses of peripheral blood lymphocytes of patients with systemic lupus erythematosus by peptides based on human and murine anti-DNA autoantibodies.

SPRY2 mediates fibroblast dysfunction and impaired wound healing in diabetic foot ulcers by blocking the Ras/MAPK axis.

Therapeutic attenuation of orbital adipogenesis via M2 macrophage exosomes: A dual inhibition of oxidative stress and autophagy.

Analysis of changes in the phenotypic profile and frequencies of peripheral blood myeloid-derived suppressor cells in patients with endometrial cancer before and after surgical treatment.

Is there a role for B cells in Alzheimer's disease?

TNF and CD107a-dominated enhanced effector responses of CD8+ MAIT cells to Escherichia coli stimulation in patients with aplastic anemia.

Hemoglobin-based oxygen carriers promote the expression of antiviral defense genes in bone marrow leukocytes.

Impella Versus Intra-aortic Balloon Pump in Cardiogenic Shock: Arrhythmias, Bleeding Complications, and In-Hospital Outcomes in a Propensity-Matched Analysis of the National Inpatient Sample.

Unsupervised Machine Learning of Intrapancreatic Fat Deposition Reveals Distinct Clinical Phenotypes: A CT Study.

Predictive value of stress-induced hyperglycemia for 28-day all-cause mortality in ICU patients with sepsis: a MIMIC-IV-based retrospective cohort study.

Layered immune biomarker monitoring in IgA nephropathy: from mucosal IgA dysregulation to precision therapeutic response assessment.

Gastrointestinal Histoplasmosis Mimicking Intestinal Tuberculosis and Crohn's Disease: Ileocecal Involvement in an Immunocompetent Host.

Peripheral immune phenotyping identifies an immunosuppressed sepsis endotype with potential relevance for immune stratification.

Related Experiment Videos

Antigenic competition and genetic control of the immune response. A hypothesis for intramolecular competition

Related Concept Videos

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