An unusual case of leukemia involving the eye: a clinico-pathological study

A patient with diverse and protracted ocular involvement with leukemia is presented. The ocular symptoms, signs, and pathology of leukemia are reviewed. Infiltration of the vitreous by leukemic cells in the absence of hemorrhage is documented for the first time. It is emphasized that ocular involvement threatening vision may occur in leukemia despite complete hematologic and bone marrow remission. It is suggested that early radiotherapy may be useful in preventing visual loss.