Jove
Visualize
Contact Us

Related Experiment Videos

The temporal sequence of synaptic initiation, crossing over and synaptic completion.

M P Maguire

    Genetics
    |March 1, 1972
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Concomitant ipsilateral floating hip and floating knee injuries: a unique injury and review of the literature.

    International journal of clinical practice·2007
    Same author

    Pathological fracture of the distal humerus treated with Nancy nails.

    Injury·2004
    Same author

    Re: A simple technique for the retention of a subcuticular suture. Singh-Ranger D. Surg J R Coll Surg Edinb Irel 2003; 1 (3): 149-51.

    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2004
    Same author

    Re: Primary total hip replacement. Surg Jr Coll Surg Edinb Irel. 1: 6; 332-341.

    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2004
    Same author

    RPR 107393, a potent squalene synthase inhibitor and orally effective cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase.

    The Journal of pharmacology and experimental therapeutics·1997
    Same author

    Nitric oxide modulates human chorionic gonadotropin-induced ovulation in the rabbit.

    Fertility and sterility·1997
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Crossover commitment in maize may occur during synaptic initiation, not just during pachytene. This challenges the idea that synapsis must be maximal before crossovers are established, suggesting earlier genetic programming.

    Area of Science:

    • Genetics
    • Molecular Biology
    • Cytogenetics

    Background:

    • The timing of crossover establishment during meiosis is debated.
    • Conventional views suggest crossovers are fixed during pachytene, after maximal synapsis.

    Purpose of the Study:

    • To test the hypothesis that crossover commitment occurs during synaptic initiation.
    • To investigate the relationship between synapsis, crossover frequency, and chromosome structure in maize.

    Main Methods:

    • Analysis of synapsis and crossover frequencies in maize chromosomes with a paracentric inversion.
    • Comparison of observed data with theoretical expectations from various hypotheses.

    Main Results:

    • Observed synapsis and crossover patterns challenge existing models.

    Related Experiment Videos

  • Complex hypotheses involving compensatory crossovers or procedural artifacts are less parsimonious.
  • Evidence suggests crossover commitment may precede or determine synaptic expression.

    • Conclusions:

    • The simplest hypothesis is that crossover commitment influences synaptic expression.
    • The role of the synaptonemal complex in establishing crossover sites may be minimal.
    • Telomere function in synaptic initiation requires further investigation and potential restrictions.