Related Experiment Video
Updated: Aug 10, 2026

21:16
An In Vitro Skin Irritation Test (SIT) using the EpiDerm Reconstructed Human Epidermal (RHE) Model
Published on: July 14, 2009
[Proposal for a method of testing the acute irritative effect of substances by experiments upon animals (author's
Abstract:
This paper deals with the test methods for the irritative effect of substances, and suggests a method for standardised determination of acute dermal I.D.50. Liquids or easily soluble substances can be checked in various concentrations with the help of an open application on rabbits.

