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Aqueous central cavity in aspartate transcarbamylase from Escherichia coli
Science (New York, N.Y.)
|February 16, 1973
Abstract:
A three-dimensional x-ray diffraction study of aspartate transcarbamylase to 5.5-angstrom resolution, with the aid of four isomorphous heavy atom derivatives, indicates the presence of a central aqueous cavity approximating an oblate spheroid about 25 by 50 by 50 angstroms in dimension, within a molecule about 90 by 110 by 110 angstroms in largest dimensions.