Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Methemoglobinemia: nitrobenzene ingestion.

M A Schimelman1, J M Soler, H A Muller

  • 1Emergency Medicine Division, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.

JACEP
|November 1, 1978
PubMed
Summary

A severe case of multiple toxin ingestion led to rapid-onset nitrobenzene-induced methemoglobinemia. Treatment with methylene blue and supportive care resulted in patient recovery from this poisoning.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sexual disorders post-stroke: Description of a cohort of patients followed in rehabilitation.

The French journal of urology·2024
Same author

Use of the ice water test as an early predictor of recovery of erectile function in patients with spinal cord injury.

Spinal cord series and cases·2020
Same author

[Is there any obstruction other than prostatic obstruction in Idiopathic Parkinson's Disease?]

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2019
Same author

Comparison of Application Methods of Systemic Fungicides to Suppress Branch Cankers in Clementine Trees Caused by Phytophthora citrophthora.

Plant disease·2019
Same author

Dartos reflex as autonomic assessment in persons with spinal cord injury.

Spinal cord series and cases·2018
Same author

Prediction of sexual function following spinal cord injury: a case series.

Spinal cord series and cases·2018

Area of Science:

  • Toxicology
  • Emergency Medicine
  • Environmental Health

Background:

  • Multiple toxin ingestion is a critical medical emergency.
  • Nitrobenzene is a component found in some industrial solvents and cleaning agents.

Observation:

  • A 48-year-old male ingested approximately 300 cc of Hoppe's Gunpower Solvent #9.
  • The solvent contained kerosene, denatured ethyl alcohol, oil, and nitrobenzene.
  • The primary clinical manifestation was rapid-onset methemoglobinemia induced by nitrobenzene.

Findings:

  • The patient presented with severe nitrobenzene-induced methemoglobinemia.
  • Treatment included 1% methylene blue and, in severe instances, hemodynamic and ventilatory support.
  • The patient recovered within 48 hours, with follow-up for mild hemolytic anemia.

Implications:

  • Prompt recognition and treatment of nitrobenzene poisoning are crucial.
  • Methylene blue is an effective antidote for methemoglobinemia.
  • Severe poisonings necessitate comprehensive medical and psychiatric follow-up.

Related Experiment Videos