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Related Experiment Videos

Travelers' diarrhea.

E Barrett-Connor

    California Medicine
    |March 1, 1973
    PubMed
    Summary
    This summary is machine-generated.

    Travelers

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    Area of Science:

    • Travel Medicine
    • Infectious Diseases
    • Gastroenterology

    Background:

    • Travelers' diarrhea affects approximately 25% of North Americans visiting developing countries.
    • Enteropathogenic Escherichia coli are a common cause of this illness.
    • Existing treatments like antimicrobials and anti-diarrheal agents are ineffective once symptoms start.

    Purpose of the Study:

    • To evaluate the efficacy of various agents for the prevention of travelers' diarrhea.
    • To assess the safety and effectiveness of chemoprophylactic strategies.

    Main Methods:

    • Review of existing literature and double-blind studies.
    • Analysis of data on the effectiveness of iodochlorhydroxyquin, furazolidone, neomycin sulfate, and phthalylsulfathiazole.
    • Consideration of general travel precautions.

    Main Results:

    • Iodochlorhydroxyquin has not proven effective and may be dangerous.
    • Furazolidone's preventive role is uncertain.
    • Neomycin sulfate and phthalylsulfathiazole demonstrated chemoprophylactic efficacy in Mexico.
    • General dietary precautions may prevent more severe illnesses.

    Conclusions:

    • Specific chemoprophylaxis with neomycin sulfate or phthalylsulfathiazole may be considered for limited travel scenarios.
    • Preventive measures should be carefully weighed against potential risks and benefits.
    • General travel advice on food and water safety remains important.

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