Related Experiment Video
Updated: Aug 9, 2026

06:09
Assaying the Kinase Activity of LRRK2 in vitro
Published on: January 18, 2012
Electrophoretic demonstration of heterozygosis in hereditary pyruvate kinase deficiency. An unusual method
Human Genetics
|April 5, 1979
Abstract:
The defective PK variant of a patient with a severe form of hemolytic anemia was characterized by its inability to undergo a normal 'proteolytic maturation.' In obligatory heterozygotes it could be proved that red cells contained different PK species, some of them sensitive and the others partially resistant to the action of trypsin.
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