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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

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Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.

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The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.

Gene·2000

Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene.

Chemistry & biology·1999

Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity.

Bio/technology (Nature Publishing Company)·1995

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The American surgeon·1990

Accelerating rise in early-onset colorectal cancer in the United States: Updated SEER trends through 2023.

American journal of surgery·2026

Novel community-based approach for enhanced postoperative follow-up in rural Sierra Leone: Is it sustainable?

American journal of surgery·2026

Perioperative selective serotonin reuptake inhibitor and serotonin-norepinephrine reuptake inhibitor use and 30-day bleeding after elective colectomy.

American journal of surgery·2026

Is longer better? A comparison of adenoma detection rates before and after the updated quality indicators for colonoscopies.

American journal of surgery·2026

Advancing health equity in Complex Abdominal & Pelvic Surgery: A 5-year report.

American journal of surgery·2026

Deletion of Annexin A2 protects from liver injury after massive small bowel resection in mice.

American journal of surgery·2026

Locations of emergency medical services attended non-fatal opioid-involved overdoses, 888 counties, USA, 2022-2024.

Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention·2026

Comparable Organic Aerosol Mass Enhancement during Photochemical and Dark Oxidation of Biomass Burning Emissions.

Environmental science & technology·2026

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The Journal of organic chemistry·2026

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Journal of environmental sciences (China)·2026

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ChemSusChem·2026

A Case of Chordoid Glioma Complicated by an Anterior Communicating Artery Aneurysm Treated with Single-Stage Surgery Combining an Interhemispheric Approach and Endoscopic Transsphenoidal Surgery.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi·2026

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Treatment of liver abscesses. A conservative surgical approach

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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.

The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.

Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene.

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