[Various mechanisms of cardiogenic shock under experimental conditions]

Study of the mechanisms of compensation derangement in cardiogenic shock in 70 anesthetized and nonanesthetized dogs irrespective of the type of its course showed that extracardiac shifts are of essential importance. In "fulgurating" shock, marked cardiac disorders may be aggravated by stimuli induced by hyperactive humoral and vascular (peripheral) reactions. In cardiogenic shock of a longer duration, the extracardiac mechanisms of decompensation are usually manifested by disorders of peripheral circulation associated with increasing hyporeactivity. With timely control the character of decompensation in cardiogenic shock may be prognosticated, which predetermines the principles of rational, pathogenetic therapy.