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Methadone.

Canadian Medical Association Journal

|October 6, 1973

Summary

This summary is machine-generated.

Methadone maintenance treatment offers a longer-acting alternative to morphine, with less intense withdrawal and improved social productivity for heroin dependence. This review highlights essential program components for successful patient outcomes.

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Area of Science:

Pharmacology and Addiction Medicine

Background:

Methadone and acetylmethadol share morphine's properties but offer extended duration and reduced withdrawal severity.
These medications can block the euphoric effects of other opiates, aiding in addiction management.

Purpose of the Study:

To review published results and procedures of methadone maintenance treatment (MMT) programs for heroin dependence.
To evaluate the effectiveness of MMT in improving patients' social productivity and employment status.

Main Methods:

Review of existing literature on methadone maintenance treatment programs.
Analysis of patient outcomes based on daily oral methadone dosages (low: 20-60 mg, high: 80-120 mg).

Main Results:

High success rates (up to 80%) reported, defined by patients being employed or socially productive.

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Key factors for success include patient selection, therapeutic facilities, supply control, and evaluation.

Conclusions:

Methadone maintenance is a viable treatment for heroin dependence, improving social functioning.
Controversies exist regarding 'drug-free' versus 'socially productive' success criteria and program administration.