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[A comparative study of iron and total iron binding capacity in the serum of patients with lymphoreticular blastomas]

Vutreshni Bolesti
|January 1, 1974
PubMed

One hundred and forty three patients with lymphoreticular blastoma were examined 97 of them with Hodgkin disease in various clinical stages, 26 patients with reticulosarcoma and 20--with lymphosarcoma. The following indices were determined in all patients; hemoglobin, serum iron, total ironbinding capacity and the degree of saturation of transferins. Low values of serum iron were found in the exacerbated stages of patients with Hodgkin, especially in III and IV clinical stage. They are decreased also in patients with reticulosarcoma but to a less degree, while in those with lymphosarcoma--they are within normal limits. The total iron binding capacity is elevated in the same stages, the saturation degree of transferins being decreased. Hemoglobin increases in the stage of clinical improvement in the patients with Hodgkin, as well as iron and saturation degree of transferins. The total iron binding capacity is decreasedmthe changes in the above indices, though not specific, were concluded to be able to serve as additional tests in the determination of the period and to a certain extent, of the stage in patients with Hodgkin as well as to make a differential diagnosis with the rest lymphoreticular blastomas.

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