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A histochemical technique for evaluation of progesterone receptors in breast cancer
Research Communications in Chemical Pathology and Pharmacology
|March 1, 1979
Abstract:
A histochemical method for the detection and localization of progesterone receptors in human breast cancer has been developed employing a fluorescein labeled conjugate of bovine serum albumin linked to a progestin as the binding hormone. Considerable tumor cell receptor heterogeneity was apparent and nuclear binding was frequently noted. The results of the new assay correlated with those obtained by dextran-coated charcoal assay in 91 per cent of specimens.