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Related Experiment Videos

Overwhelming pneumococcaemia 17 years after splenectomy. A case report.

R Sher, C S Block, E D Gomperts

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |April 14, 1979
    PubMed
    Summary

    Fulminant pneumococcaemia and disseminated intravascular coagulopathy occurred in a young adult 17 years post-splenectomy. Vaccination is crucial for preventing severe infections in asplenic patients.

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    Area of Science:

    • Infectious Diseases
    • Hematology

    Background:

    • Splenectomy increases susceptibility to encapsulated bacterial infections.
    • Overwhelming post-splenectomy infection (OPSI) is a rare but severe complication.

    Observation:

    • A young adult male, 17 years post-splenectomy, presented with fulminant Streptococcus pneumoniae sepsis.
    • The patient developed disseminated intravascular coagulopathy (DIC).

    Findings:

    • Clinical, laboratory, and postmortem findings confirmed pneumococcaemia and DIC.
    • Prompt diagnosis and management are critical for asplenic individuals.

    Implications:

    • This case highlights the long-term risk of OPSI in asplenic patients.
    • Pneumococcal and other relevant vaccines are vital for prophylaxis in asplenic populations.

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  • Enhanced surveillance and vaccination strategies are essential for asplenic patient care.