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Related Experiment Videos

Two years' experience with Rh hemolytic disease reporting.

W E Hawes, V L Mordaunt

    California Medicine
    |May 1, 1973
    PubMed
    Summary

    California

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    Cesarean section, fetal monitoring, and perinatal mortality in California.

    American journal of public health·1979

    Area of Science:

    • Perinatal Medicine
    • Public Health Surveillance
    • Immunology

    Background:

    • California law mandates Rho(D) testing for all pregnant women since 1970.
    • Reporting of Rho(D) Hemolytic Disease of the Newborn (HDN) to the State Department of Public Health is required.
    • Accurate morbidity and mortality data for Rho(D) HDN in California are crucial for assessing intervention effectiveness.

    Purpose of the Study:

    • To analyze the incidence and mortality trends of Rho(D) Hemolytic Disease of the Newborn in California.
    • To evaluate the impact of public health interventions and the use of anti-Rho(D) immune globulin.
    • To provide accurate epidemiological data on Rho(D) HDN.

    Main Methods:

    • Analysis of mandatory reporting data for Rho(D) HDN cases and outcomes in California.
    • Review of historical data since 1950 to identify trends.
    • Comparison of recent data with literature and other state health departments.

    Main Results:

    • A precipitous fall in Rho(D) HDN deaths and cases observed in the past two years.
    • Significant decrease in HDN incidence and mortality following the implementation of reporting and widespread anti-Rho(D) immune globulin use.
    • California's reporting law provides accurate, comprehensive data on Rho(D) HDN trends.

    Conclusions:

    • Mandatory testing, routine anti-Rho(D) immune globulin administration, early treatment, and reduced family size have dramatically decreased Rho(D) HDN.
    • California's public health initiatives have led to accurate tracking and a significant reduction in Rho(D) HDN morbidity and mortality.
    • The study highlights the success of a comprehensive public health approach in managing and preventing Rho(D) Hemolytic Disease of the Newborn.

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