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Published on: February 26, 2019
[Examination of hormonal contraceptives by enzyme induction (author's transl)]
Zentralblatt Fur Gynakologie
|January 1, 1979
Abstract:
The influence of drug stimulated biotransformation on the biological effectiveness of two different contraceptives (Deposition and Gravistat) was observed.--Phenobarbital, a potent enzyme inducer, is known to increase the metabolism of steroid hormones, including estrogens and progrestogens. -- The clinical symptoms of drug mediated enzyme induction of hormonal steroid contraceptives are dysfunctional bleedings. This phenomenon is discussed.
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