[Radioimmunological LH and FSH determination from urine collected within 24 hours]

Sensitive radioimmunoassays for measurement of urinary human LH and FSH by using either pituitary or urinary LH and FSH standard preparations are described. In healthy subjects mean LH and FSH values in 24-h-urine specimens were determined which are similar to those reported by others: LH: 22.6 IU/24-h (males), 17.8 IU/24-h (females), 49.1 IU/24-h (postmenopausal females); FSH: 6.0 IU/24-h (males), 15.0 IU/24 h (females), 48.5 IU/24-h (postmenopausal females). Because of the high sensitivity and practibility we believe that these radioimmunoassays are clinically useful approaches in assessment of pituitary and gonadal disorders.