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Hypertension among Aleuts.

E F Torrey, F M Reiff, G R Noble

    American Journal of Epidemiology
    |July 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Hypertension is highly prevalent among Aleut populations in Alaska, with rates remaining consistently high over a decade. This suggests a widespread issue potentially linked to genetics, lifestyle, and environmental factors like cadmium in seal liver.

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    Area of Science:

    • Environmental Health
    • Epidemiology
    • Nutritional Science

    Background:

    • High prevalence of hypertension observed in Aleut populations on St. Paul Island, Alaska.
    • Hypertension rates remained elevated over a 10-year survey period (1966-1976).
    • Preliminary data suggests this high prevalence may extend to other Aleut villages in the Aleutian Chain.

    Purpose of the Study:

    • To investigate the prevalence of hypertension in Aleut communities.
    • To explore potential etiological factors contributing to hypertension in this population.
    • To highlight the unique research potential of isolated locations like St. Paul Island.

    Main Methods:

    • Conducted surveys on St. Paul Island in 1966 and 1976 to assess hypertension prevalence.
    • Collected preliminary data from other Aleut villages.

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  • Analyzed potential etiological factors including genetics, obesity, salt intake, and cadmium levels in dietary staples.

    • Main Results:

    • Hypertension prevalence in the surveyed Aleut population was among the highest reported in the United States.
    • Consistently high rates were observed over the 10-year study period.
    • Elevated cadmium levels were detected in seal livers, a significant dietary component.

    Conclusions:

    • Hypertension appears to be a widespread health concern in Aleut communities.
    • A complex interplay of genetic factors, obesity, high salt intake, and environmental cadmium exposure likely contributes to the high prevalence.
    • Isolated Aleut communities serve as valuable natural laboratories for studying complex disease etiologies.