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Related Experiment Videos

Species differences in cardiac energetics.

D S Loiselle, C L Gibbs

    The American Journal of Physiology
    |July 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Cardiac energy flux in rat, guinea pig, and cat papillary muscles shows size-dependent variations. Contrary to dimensional arguments, cardiac energy expenditure is not directly proportional to heart rate across species.

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    Area of Science:

    • Comparative physiology
    • Cardiac mechanics
    • Bioenergetics

    Background:

    • Understanding cardiac energy expenditure across species is crucial for comparative physiology.
    • Previous dimensional arguments suggested a direct proportionality between cardiac energy expenditure and heart rate.
    • Species-specific differences in cardiac metabolism and body size influence energy flux.

    Purpose of the Study:

    • To measure the energy flux of mammalian papillary muscles under various conditions.
    • To compare cardiac energy expenditure across different species (rat, guinea pig, cat).
    • To investigate the relationship between cardiac energy expenditure, heart rate, and body size.

    Main Methods:

    • Myothermic measurements of energy flux in rat, guinea pig, and cat papillary muscles.

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  • Experiments conducted under resting, isometric, and isotonic conditions at 27°C.
  • Comparison of myothermic data with literature values for cardiac oxygen consumption.

    • Main Results:

    • Resting heat rate was inversely related to body size.
    • The isometric heat-stress relationship slope was constant, but the stress-independent heat component was lowest in rats.
    • Maximum mechanical efficiency occurred at lighter loads, and rat muscles showed higher active efficiency but also higher basal heat rate.

    Conclusions:

    • Cardiac energy expenditure is not directly proportional to heart rate across species, challenging common dimensional arguments.
    • Smaller species likely have a lower ratio of cardiac energy metabolism to total body metabolism (EH/EB).
    • Myothermic data provide insights into the bioenergetics of cardiac muscle across different mammalian species.