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Gastric 'flu influenza B causing abdominal symptons in children
Lancet (London, England)
|February 8, 1975
Summary
Influenza B virus infection in children often presents with severe abdominal pain, mimicking appendicitis, and less prominent respiratory symptoms. Immunofluorescence is a reliable diagnostic method for rapid identification.
Area of Science:
- Pediatric Infectious Diseases
- Virology
- Epidemiology
Background:
- Influenza B virus causes significant pediatric illness, with detailed symptomatology often underreported.
- Previous studies lacked comprehensive assessment of Influenza B clinical manifestations in hospitalized children.
- Accurate and rapid viral diagnosis is crucial for effective patient management and infection control.
Purpose of the Study:
- To detail the clinical symptomatology of Influenza B virus infection in hospitalized children.
- To evaluate the reliability and utility of the immunofluorescent method for Influenza B diagnosis.
- To assess the impact of rapid diagnosis on clinical management and hospital cross-infection control.
Main Methods:
- Identification of Influenza B virus in 102 hospitalized children during 1973-1974 epidemics.
- Detailed clinical assessment of symptoms, including abdominal pain, respiratory involvement, convulsions, and myalgia.
- Comparison of immunofluorescence diagnostic technique with standard virus isolation methods.
Main Results:
- Abdominal pain, sometimes severe, was a dominant symptom, particularly in older children.
- Respiratory symptoms were often mild, though lower respiratory tract involvement occurred.
- Immunofluorescence showed 97.5% copositivity with standard isolation, proving reliable for Influenza B diagnosis.
Conclusions:
- Influenza B virus infection in children can manifest with prominent abdominal pain, necessitating careful clinical evaluation.
- The immunofluorescent method offers a reliable and rapid diagnostic tool for Influenza B.
- Rapid diagnosis aids clinical decision-making, patient management, and prevention of nosocomial spread.