Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene

The involvement of a 'bay-region' and a non-'bay-region' diol-epoxide in the metabolic activation of benz[a]anthracene in mouse skin and in hamster embryo cells.

Carcinogenesis·2012

Reactions of 'bay-region' and non-'bay-region' diol-epoxides of benz(a)anthracene with DNA: evidence indicating that the major products are hydrocarbon-N2-guanine adducts.

Carcinogenesis·2012

Metabolic activation of benz(a)anthracene: fluorescence spectral evidence indicates the involvement of a non-'bay-region' diol-epoxide.

Carcinogenesis·2012

Liver microsome-mediated mutagenicity of dihydrodiols derived from dibenz(a,c)anthracene in S. typhimurium TA100.

Carcinogenesis·2012

The expression of xenobiotic-metabolizing enzymes in human prostate and in prostate epithelial cells (PECs) derived from primary cultures.

The Prostate·2006

Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon.

British journal of cancer·2005

TMEM63B as a dual-function mechanosensitive channel and lipid scramblase: structural insights, physiological roles, and pharmacological potential.

Biochemical pharmacology·2026

Inhibition of neutrophil extracellular trap formation ameliorates astrocyte pyroptosis via CUL7-dependent NLRP3 ubiquitination in mice with sepsis-associated encephalopathy.

Biochemical pharmacology·2026

cGAS-STING activation promotes abdominal aortic aneurysm formation in mice and humans: Therapeutic potential of inhibition.

Biochemical pharmacology·2026

Gramine limits alcohol-associated liver injury by suppressing NOX1-linked ferroptotic responses and mitochondrial dysfunction.

Biochemical pharmacology·2026

D14, a β-carboline alkaloid derivative of dehydrocrenatidine, exerts anti-glioma effect by targeting SRC.

Biochemical pharmacology·2026

Withaferin A induces apoptosis and ferroptosis in gastric cancer cells via ROS-mediated mitochondrial damage and the Keap1/Nrf2/HO-1/GPX4 axis.

Biochemical pharmacology·2026

A high-level theoretical study of the C2H4 + OH reaction.

Physical chemistry chemical physics : PCCP·2026

Position-Specific Carbon Isotope Constraints on Propane Formation from Kerogen during Open-System Pyrolysis.

ACS omega·2026

The delocalized nature of chemical bonding at a catalytic metal surface.

Science (New York, N.Y.)·2026

Clinical and Psychological Impact of Pruritus Related to Skin Barrier Damage.

American journal of clinical dermatology·2026

Modeling of Surface Tension Isotherms with an Extremum for Binary Liquid Mixtures.

The journal of physical chemistry. B·2026

Optimization of electrochemical reduction of high-pressure CO2 to hydrocarbon (methane) at nickel electrode in cold methanol.

RSC advances·2026

Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene

Related Experiment Videos

Related Concept Videos

The involvement of a 'bay-region' and a non-'bay-region' diol-epoxide in the metabolic activation of benz[a]anthracene in mouse skin and in hamster embryo cells.

Reactions of 'bay-region' and non-'bay-region' diol-epoxides of benz(a)anthracene with DNA: evidence indicating that the major products are hydrocarbon-N2-guanine adducts.

Metabolic activation of benz(a)anthracene: fluorescence spectral evidence indicates the involvement of a non-'bay-region' diol-epoxide.

Liver microsome-mediated mutagenicity of dihydrodiols derived from dibenz(a,c)anthracene in S. typhimurium TA100.

The expression of xenobiotic-metabolizing enzymes in human prostate and in prostate epithelial cells (PECs) derived from primary cultures.

Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon.

TMEM63B as a dual-function mechanosensitive channel and lipid scramblase: structural insights, physiological roles, and pharmacological potential.

Inhibition of neutrophil extracellular trap formation ameliorates astrocyte pyroptosis via CUL7-dependent NLRP3 ubiquitination in mice with sepsis-associated encephalopathy.

cGAS-STING activation promotes abdominal aortic aneurysm formation in mice and humans: Therapeutic potential of inhibition.

Gramine limits alcohol-associated liver injury by suppressing NOX1-linked ferroptotic responses and mitochondrial dysfunction.

D14, a β-carboline alkaloid derivative of dehydrocrenatidine, exerts anti-glioma effect by targeting SRC.

Withaferin A induces apoptosis and ferroptosis in gastric cancer cells via ROS-mediated mitochondrial damage and the Keap1/Nrf2/HO-1/GPX4 axis.

A high-level theoretical study of the C2H4 + OH reaction.

Position-Specific Carbon Isotope Constraints on Propane Formation from Kerogen during Open-System Pyrolysis.

The delocalized nature of chemical bonding at a catalytic metal surface.

Clinical and Psychological Impact of Pruritus Related to Skin Barrier Damage.

Modeling of Surface Tension Isotherms with an Extremum for Binary Liquid Mixtures.

Optimization of electrochemical reduction of high-pressure CO2 to hydrocarbon (methane) at nickel electrode in cold methanol.

Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene

Related Experiment Videos

Related Concept Videos

Related Articles