[Electromechanical model of an enzyme-substrate kompleksa]

An electro-mechanical model is suggested for studying the hydrolytic reaction catalyzed by an enzyme having a domain structure. The fixation of the necessary set of reagents configurations by the enzyme molecule allows the reaction rate acceleration. The model suggests specificity of the enzyme action. The model makes more clear the phenomenon of complementarity between the unchanging part of the substrate molecule and the active site of the enzyme which require not only the spatial fit but also the agreement of some physical properties, such as atom and group partial charges. The model is selfconsistent, i. e. it is not contrary to the existing data on the structural and functional properties of enzyme proteins having the domain structure.