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Allergens in sesame oil contact dermatitis
Acta Dermato-Venereologica
|January 1, 1975
Summary
Sesame oil allergy is linked to specific compounds. Studies identified sesamol, sesamin, and sesamolin as allergens in patients with contact allergy to sesame oil, with sesamolin and sesamin being the most common triggers.
Area of Science:
- Dermatology
- Allergology
- Chemical analysis of natural products
Background:
- Contact allergy to sesame oil affects numerous patients.
- The specific allergens responsible for sesame oil allergy require detailed investigation.
Purpose of the Study:
- To identify the specific chemical compounds in sesame oil that cause contact allergy.
- To determine the prevalence of allergy to individual sesame oil components.
Main Methods:
- Analysis of crude and purified sesame oil for allergen identification.
- Patch testing with sesame oil components on patients with suspected allergy.
Main Results:
- Sesamol, sesamin, and sesamolin were identified in sesame oil.
- 12 out of 13 patients showed positive patch test reactions to sesamolin and sesamin.
- 8 out of 13 patients reacted positively to sesamol.
Conclusions:
- Sesamolin and sesamin are significant allergens in sesame oil contact allergy.
- Sesamol also contributes to allergic reactions, though less frequently than sesamolin and sesamin.
- Further investigation is needed to differentiate allergenicity between related sesamol compounds.