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Updated: Aug 15, 2026

Measurement of Basal and Forskolin-stimulated Lipolysis in Inguinal Adipose Fat Pads
Published on: July 21, 2017
Free fatty acid release from human adipose tissue in relation to obesity -- effect of isoprenaline
Abstract:
The capacity to release non-esterified acids and glycerol from the abdominal subcutaneous adipose tissue into a medium containing different concentrations of isoprenaline was studied in 21 adults with different body weight (14 obese, 7 controls). The obese had a significantly lower maximum adipokinetic capacity (expressed as pD2) than controls. The significant decrease in pD2 in the obese was found to depend on the stabilization of the weight while the dynamic pD2 stage values of the obese did not differ from those of controls. The hypothesis is expressed that lower pD2 values may be related to the smaller decrease of body fat during weight reduction.
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