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Related Experiment Videos

Thalassaemia in Cyprus.

T Ashiotis, Z Zachariadis, K Sofroniadou

    British Medical Journal
    |April 7, 1973
    PubMed
    Summary

    Cyprus has the highest frequencies of thalassaemia genes in Caucasians. 15% of Greek and Turkish Cypriots carry beta-thalassaemia, and 10% carry alpha-thalassaemia.

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    Area of Science:

    • Medical Genetics
    • Hematology
    • Public Health

    Background:

    • Thalassaemias are inherited blood disorders.
    • High carrier rates can pose public health challenges.

    Purpose of the Study:

    • To determine the frequencies of beta-thalassaemia and alpha-thalassaemia in Cyprus.
    • To compare Cyprus's thalassaemia gene frequencies with other Caucasian populations.

    Main Methods:

    • Survey of hospital inpatients.
    • Hematological investigations of adult and newborn population samples.

    Main Results:

    • 15% of Greek and Turkish Cypriots are carriers of beta-thalassaemia genes.
    • 10% of the population carry alpha-thalassaemia genes.
    • Cyprus exhibits the highest known frequencies of thalassaemia genes among Caucasian populations.

    Conclusions:

    • Cyprus has a significant burden of thalassaemia gene carriers.
    • These findings highlight the need for genetic counseling and screening programs in Cyprus.