Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Necrotizing enterocolitis in neonates fed human milk.

R M Kliegman, W B Pittard, A A Fanaroff

    The Journal of Pediatrics
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clinical trial of tin mesoporphyrin to prevent neonatal hyperbilirubinemia.

    Journal of perinatology : official journal of the California Perinatal Association·2016
    Same author

    Recent evidence based advances in neonatology.

    Early human development·2012
    Same author

    Effects of delayed cord clamping in very-low-birth-weight infants.

    Journal of perinatology : official journal of the California Perinatal Association·2011
    Same author

    To Phil Sunshine, MD, with admiration.

    Journal of perinatology : official journal of the California Perinatal Association·2011
    Same author

    Meconium aspiration syndrome: historical aspects.

    Journal of perinatology : official journal of the California Perinatal Association·2008
    Same author

    Association between early postnatal weight loss and death or BPD in small and appropriate for gestational age extremely low-birth-weight infants.

    Journal of perinatology : official journal of the California Perinatal Association·2007

    Refrigerated human milk did not reduce necrotizing enterocolitis (NEC) rates in neonates. Infants fed human milk were smaller, less mature, and fed later than formula-fed infants, yet NEC onset was similar across groups.

    Area of Science:

    • Neonatal Medicine
    • Pediatric Gastroenterology
    • Infant Nutrition

    Background:

    • Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease in premature infants.
    • Human milk is often recommended for premature infants, but its protective effect against NEC when refrigerated is debated.

    Purpose of the Study:

    • To evaluate the incidence of NEC in neonates fed exclusively refrigerated human milk compared to those fed formula.
    • To assess if refrigerated human milk impacts the timing or severity of NEC onset.

    Main Methods:

    • Retrospective analysis of neonates divided into three feeding groups: refrigerated human milk, human milk and formula, and formula alone.
    • Comparison of NEC incidence, patient characteristics (gestational age, birth weight, Apgar scores), and timing of feeding and NEC onset.

    Related Experiment Videos

    Main Results:

    • The incidence of NEC was comparable across all three feeding groups.
    • Neonates fed refrigerated human milk were significantly smaller, less mature, had lower Apgar scores, and were fed later than formula-fed infants.
    • Mean age of NEC onset and time from first feeding to NEC onset were similar among groups.

    Conclusions:

    • Refrigerated human milk was not effective in reducing the incidence of NEC in this cohort of neonates.
    • Potential factors contributing to NEC in human milk-fed infants include pathogen contamination, inadequate antigenic stimulation, or storage-related alterations in milk properties.