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Published on: October 29, 2014

Neonatal meningitis caused by Citrobacter koseri

R J Gross, B Rowe, J A Easton

    Journal of Clinical Pathology
    |February 1, 1973
    PubMed

    Insights

    Neonatal meningitis caused by Citrobacter koseri occurred in a premature baby unit, with two fatal cases. Investigations revealed two distinct strains of the bacterium, highlighting a potential outbreak.

    Area of Science:

    • Neonatalogy
    • Infectious Diseases
    • Microbiology

    Background:

    • Neonatal meningitis poses a significant threat to premature infants.
    • Outbreaks of bacterial meningitis in neonatal intensive care units require prompt investigation.

    Purpose of the Study:

    • To report on a cluster of neonatal meningitis cases.
    • To identify the causative agent and its characteristics.

    Main Methods:

    • Cerebrospinal fluid samples were collected from affected neonates.
    • Bacterial isolates underwent detailed biochemical and serological analysis.

    Main Results:

    • Citrobacter koseri was identified as the causative agent in all four cases.
    • Two distinct bioserotypes of Citrobacter koseri were identified.
    • Two of the three initial cases were fatal.

    Conclusions:

    • Citrobacter koseri can cause severe neonatal meningitis outbreaks.
    • The presence of distinct bioserotypes suggests a complex transmission or source.
    • Effective infection control measures are crucial in neonatal units.

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