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Neonatal meningitis caused by Citrobacter koseri.
Journal of Clinical Pathology
|February 1, 1973
Summary
Neonatal meningitis caused by Citrobacter koseri occurred in a premature baby unit, with two fatal cases. Investigations revealed two distinct strains of the bacterium, highlighting a potential outbreak.
Area of Science:
- Neonatalogy
- Infectious Diseases
- Microbiology
Background:
- Neonatal meningitis poses a significant threat to premature infants.
- Outbreaks of bacterial meningitis in neonatal intensive care units require prompt investigation.
Purpose of the Study:
- To report on a cluster of neonatal meningitis cases.
- To identify the causative agent and its characteristics.
Main Methods:
- Cerebrospinal fluid samples were collected from affected neonates.
- Bacterial isolates underwent detailed biochemical and serological analysis.
Main Results:
- Citrobacter koseri was identified as the causative agent in all four cases.
- Two distinct bioserotypes of Citrobacter koseri were identified.
- Two of the three initial cases were fatal.
Conclusions:
- Citrobacter koseri can cause severe neonatal meningitis outbreaks.
- The presence of distinct bioserotypes suggests a complex transmission or source.
- Effective infection control measures are crucial in neonatal units.