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Creatine phosphokinase elevation in a case of tick paralysis
Canadian Medical Association Journal
|April 7, 1973
Summary
A child experienced tick paralysis from a Dermacentor andersoni tick bite, showing limb weakness and breathing difficulties. Elevated plasma creatine phosphokinase (CPK) levels were the only abnormal lab finding during paralysis.
Area of Science:
- Neurology
- Toxicology
- Pediatrics
Background:
- Tick paralysis is a rare neurological disorder caused by toxins in tick saliva.
- Dermacentor andersoni ticks are known vectors for various diseases, including tick paralysis.
Purpose of the Study:
- To describe a case of tick paralysis in a pediatric patient.
- To report clinical findings and diagnostic results associated with tick paralysis.
Main Methods:
- Clinical case study of a female child presenting with paralysis.
- Physical examination and diagnostic laboratory tests were performed.
- Analysis of plasma creatine phosphokinase (CPK) levels.
Main Results:
- The patient presented with paralysis of lower limbs, respiratory distress, and arm weakness.
- A single Dermacentor andersoni tick was identified as the cause.
- Elevated plasma creatine phosphokinase (CPK) activity was the sole abnormal laboratory finding, persisting for 10 days.
Conclusions:
- Tick paralysis should be considered in cases of acute, unexplained neurological deficits in children.
- Elevated CPK levels may serve as a biomarker for tick paralysis.
- Prompt identification and removal of the tick are crucial for recovery.