[The effect of etofibrate on serum cholesterol and triglycerides (author's transl)]

Etofibrate retard administered in a daily dose 500 mg to 14 outpatients with hyperlipoproteinemia type IIa decreased the cholesterol only 1.7% after a treatment period of 6 weeks. After a treatment of 12 weeks the serum cholesterol was higher in 10 of the 14 patients than in the pretreatment period. Of low grade was the effect of etofibrate retard in 6 patients with type IIb or IV. The triglycerides decreased from 564 mg/dl to 455 mg/dl in the mean. The effect of this double ester from clofibrinic and nicotinic acid (59% to 41%) is uncertain in HLP type IIa, IIb and IV in the recommended dose of 500 mg/day.