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Updated: Jul 7, 2026

Measurement of Heme Synthesis Levels in Mammalian Cells
Published on: July 9, 2015
Dynamics of carbon monoxide binding by heme proteins
Abstract:
Rebinding of carbon monoxide to myoglobin and to cytochrome P-450 after removal by a light flash occurs down to 50 degrees K for myoglobin and 25 degrees K for cytochrome P-450 in glycerol-water solution. Above 240 degrees K the reaction is second order; between 240 degrees and 200 degrees K the rebinding becomes exponential and independent of the carbon monoxide concentration. Below 150 degrees K the reaction follows a power law and is approximately 10(3) times faster for cytochrome P-450 than for myoglobin.
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