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Inhibition by acetaldehyde of the pyruvate dehydrogenase complex from ox brain and ox kidney
The Biochemical Journal
|February 1, 1973
Abstract:
Low concentrations of acetaldehyde, similar to those that can occur in the brain of ethanol-treated animals, effectively inhibit the pyruvate dehydrogenase complex purified from ox brain or from ox kidney, although the precise mechanism of this inhibition remains to be defined.