Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human language cortex: localization of memory, syntax, and sequential motor-phoneme identification systems.

G Ojemann, C Mateer

    Science (New York, N.Y.)
    |September 28, 1979
    PubMed
    Summary

    This study mapped the human language cortex, revealing distinct systems for speech production, understanding, and verbal memory. These systems are interconnected within the peri-Sylvian region, highlighting functional specialization.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Server-based approach to web visualization of integrated 3-D medical image data.

    Proceedings. AMIA Symposium·2002
    Same author

    Functional roles of Broca's area and SMG: evidence from cortical stimulation mapping in a deaf signer.

    NeuroImage·1999
    Same author

    Visualization-based mapping of language function in the brain.

    NeuroImage·1998
    Same author

    Evaluation of a visualization-based approach to functional brain mapping.

    Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium·1997
    Same author

    Quantitative dendritic and spine analyses of speech cortices: a case study.

    Brain and language·1993
    Same author

    Background and initial case studies into the effects of prospective memory training.

    Brain injury·1992

    Area of Science:

    • Neuroscience
    • Linguistics
    • Cognitive Science

    Background:

    • The human language cortex, particularly the peri-Sylvian region, is crucial for complex linguistic functions.
    • Understanding the precise functional subdivisions within this region remains an active area of research.

    Purpose of the Study:

    • To delineate functional subdivisions within the human peri-Sylvian language cortex using direct brain stimulation.
    • To identify distinct neural systems supporting language production, comprehension, and verbal memory.

    Main Methods:

    • Direct cortical stimulation mapping was performed during craniotomies under local anesthesia.
    • Testing included naming, reading, short-term verbal memory, orofacial movements, and phoneme identification.

    Related Experiment Videos

    Main Results:

    • Sequential orofacial movements and phoneme identification were impaired at common sites, indicating a shared system for language production and understanding.
    • This language system was found to surround a motor speech pathway and be bordered by a distinct verbal memory system.
    • Specific sites affected only naming or reading, suggesting roles in syntax and higher-level language processing.

    Conclusions:

    • The peri-Sylvian language cortex exhibits distinct, interconnected functional subdivisions for speech production, comprehension, and verbal memory.
    • A common system for language production and understanding is identified, closely linked to motor pathways and distinct from verbal memory.
    • These findings contribute to a more refined map of the neural basis of human language.