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Related Experiment Videos

Cutaneous horns: a histopathologic study.

R H Schosser, S J Hodge, C R Gaba

    Southern Medical Journal
    |September 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

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    Cutaneous horns are rarely malignant, often arising from actinic keratoses. This study analyzed 230 cases, finding most horns benign but highlighting the need for adequate biopsies for diagnosis.

    Area of Science:

    • Dermatology
    • Pathology

    Background:

    • Cutaneous horns are a clinical finding, not a specific diagnosis.
    • The underlying histology of cutaneous horns can vary significantly.

    Purpose of the Study:

    • To analyze the histological findings of 230 cutaneous horns.
    • To determine the frequency of malignancy and common underlying pathologies.

    Main Methods:

    • Retrospective review of 230 cutaneous horn cases.
    • Histopathological examination of biopsy specimens.

    Main Results:

    • Fewer than one-fourth of the 230 cutaneous horns were malignant.
    • Actinic keratoses were the most common underlying lesion (37.39%).
    • Other reported underlying lesions included benign lichenoid keratosis, epidermolytic hyperkeratosis, trichilemmoma, epidermal inclusion cyst, and benign fibroma.

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    Conclusions:

    • Cutaneous horns are predominantly benign lesions.
    • Actinic keratoses are the most frequent precursor.
    • Adequate biopsy depth is crucial for accurate diagnosis.