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Regulation of muscle acetylcholine sensitivity by muscle activity in cell culture
Science (New York, N.Y.)
|July 6, 1973
Abstract:
Muscle in tissue culture provides a good system for studying longterm changes in surface membrane acetylcholine sensitivity. Muscle fibers stimulated intermittently over prolonged periods are less sensitive to iontophoretically applied acetylcholine and bind less (125)I-labeled alpha-bungarotoxin than inactive fibers.