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Oxime derivatives of erythromycin: inhibitors of Rous sarcoma virus reverse transcriptase activity and focus
The Journal of General Virology
|January 1, 1975
Abstract:
9-O-methyloximd erythromycin A and its analogue inhibited reverse transcriptase and blocked focus formation of Rous sarcoma virus. These chemicals inhibited neither DNA-dependent DNA polymerase nor DNA-dependent RNA polymerase from bacterial sources. However, they inhibited reverse transcriptase with an apparently differnt mechanism than that by rifamycin ABDP.