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Updated: Aug 10, 2026

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
Published on: May 26, 2015
[Modern aspects of the physiopathology of arteriosclerosis obliterans]
Abstract:
In a shortened survey new points of view concerning the pathophysiology of disturbances of the peripheral arterial blood supply are discussed. Here the author deals in short with the new hypothesis of the atherogenesis, according to which on the basis of a lesion of the endothelium an aggregation of thrombocytes with following stimulation of the smooth muscle cells of the media develops. The haemodynamic changes by vascular stenoses and obstructions with the possibilities of their recognition are discussed in detail, in which especially examinations under load and phasic measurements of flow are taken into consideration.
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