Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Parathyroid hormone secretion after operative bone trauma.

A Hulth, O Johnell

Acta Orthopaedica Scandinavica

|June 1, 1979

Summary

Skeletal trauma, including scoliosis surgery and femoral shortening, significantly elevates parathyroid hormone levels for over a week post-operation. This trauma also causes a drop in serum calcium, linked to reduced serum albumin levels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Identical genotypes of community-associated MRSA (ST59) and livestock-associated MRSA (ST9) in humans and pigs in rural China.

Zoonoses and public health·2018

Same author

Syndromic surveillance of influenza activity in Sweden: an evaluation of three tools.

Epidemiology and infection·2014

Same author

First European guidelines on syndromic surveillance in human and animal health published.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2014

Same author

Syndromic surveillance for local outbreak detection and awareness: evaluating outbreak signals of acute gastroenteritis in telephone triage, web-based queries and over-the-counter pharmacy sales.

Epidemiology and infection·2013

Same author

Web query-based surveillance in Sweden during the influenza A(H1N1)2009 pandemic, April 2009 to February 2010.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2011

Same author

European institutes for disease prevention and control collaborate to improve public health surveillance.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2011

Area of Science:

Orthopedic Surgery
Endocrinology
Skeletal Trauma Research

Background:

Skeletal trauma can impact hormonal balance and serum calcium levels.
Understanding the endocrine response to surgical orthopedic procedures is crucial for patient management.

Purpose of the Study:

To investigate the parathyroid hormone (PTH) secretion and serum calcium changes following skeletal trauma in humans.
To correlate these changes with specific orthopedic operations like scoliosis correction and femoral shortening.

Main Methods:

Observational study monitoring patients undergoing orthopedic surgery for skeletal trauma.
Measurement of parathyroid hormone and serum calcium levels pre- and post-operatively.
Assessment of serum albumin levels to understand calcium regulation.

Main Results:

A significant increase in parathyroid hormone secretion was observed starting the day after surgery and persisting for over a week.
A concurrent decrease in serum calcium levels was noted post-operation.
The observed hypocalcemia was dependent on the postoperative reduction in serum albumin.

Conclusions:

Skeletal trauma from major orthopedic operations triggers a sustained increase in parathyroid hormone.
Postoperative hypocalcemia following skeletal trauma is influenced by changes in serum albumin levels.
These findings highlight the complex endocrine and metabolic responses to surgical skeletal trauma.

Related Experiment Videos