Epidemic conjunctivitis: discovery of a new aetiologic agent

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

The Centers for Disease Control and Prevention (CDC) recommends that healthcare providers perform screening tests on patients with symptoms of COVID-19 in an isolated room to protect other patients from potential exposure to the virus. 
The Smart Pod, a rapidly deployable medical facility that was designed in the wake of the Ebola virus, can serve as a biocontainment unit for airborne pathogens. This emergency solution has been developed by Baylor College of Medicine as a nimble,...

In this protocol, we describe a technique to discover Zika virus specific diagnostic peptides using a high-density peptide microarray. This protocol can readly be adapted for other emerging infectious...

This protocol describes the preparation and characterization of a dendrimeric magnetic resonance imaging (MRI) contrast agent that carries cyclen-based macrocyclic chelates coordinating paramagnetic gadolinium ions. In a series of MRI experiments in vitro, this agent produced an amplified MRI signal when compared to the commercially available monomeric...

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...