Sensitization of the submaxillary gland of the rat after sympathetic denervation

The sensitivity of the submaxillary gland of the rat to chemical stimuli was examined 1, 4 and 6 weeks after sympathetic denervation. The gland was found to have developed a supersensitivity not only to noradrenaline but also, in contrast to previous reports, to adrenaline and methacholine. The supersensitivity remained unaltered throughout the period of observation.